Dangers Of Mixing Xanax (Alprazolam) And Weed

Xanax and weed (marijuana) can mix, but the combination of these two drugs can cause uncomfortable and dangerous side effects. Mixing alprazolam with marijuana may increase your risk for overdose or death.

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Dr. Manish Mishra, MBBS

Medically Reviewed By: Manish Mishra, MBBS


Xanax and marijuana are prescription medications that can help treat anxiety and panic disorders.

The two drugs are legal. And people may combine the two central nervous system depressants in the hopes of getting compounding results.

Addiction, abuse, and life-threatening health conditions may result from taking alprazolam with cannabis, as well as mixing Xanax and other drugs.

What Happens When You Mix Xanax With Weed?

Combining Xanax and weed can have a number of effects, some of which may be dangerous to your health or safety.

Central Nervous System Depression

Xanax interacts dangerously with CBD, opioids, alcohol, and other central nervous system depressants.

Smoking weed, in particular, can impact CNS efficacy by increasing the amount of benzodiazepines in the blood. This is because it makes it more difficult for the body to break down Xanax.

Memory Impairment

Marijuana use can impair various cognitive functions, from basic motor coordination to more complex executive function tasks, like the ability to control behavior, plan and organize, and solve problems.

Taking cannabis with Xanax, which also impairs cognitive function, could worsen these effects.

Both drugs contain compounds that interfere with neural signaling by binding to receptors in the brain that are involved in memory storage and processing.

Severe Drowsiness

Both weed and Xanax have sedative effects. Xanax is known to make a person feel calm, and it induces sleep.

THC in weed activates the cannabinoid receptor, causing the receptor to transmit messages to your body that induce sleep and encourage deeper sleep.

Weed also causes more Xanax to remain in the body, resulting in the sense of calm, slumber, and exhaustion. All these effects may lead to severe drowsiness.

Motor Coordination Impairment

Motor coordination and concentration problems are common side effects of Xanax. Marijuana can also impair the ability to think clearly and control movements.

Even if a person doesn’t feel high after smoking weed or ingesting higher doses of THC, their motor skills can be negatively affected.

Motor coordination and skills will suffer if the two CNS suppressants are combined.

Risks Of Mixing Xanax With Weed

The combination of benzos, such as Xanax and Valium, and marijuana can lead to overdose.

When Xanax and marijuana are combined, there is a risk of mental health complications. Possible symptoms include anxiety, hallucinations, and paranoia.

Other dangers of mixing alprazolam and weed include:

  • accidents resulting from excessive sleepiness
  • lower heart rate
  • impaired judgment
  • increased panic attacks
  • slurred speech
  • low respiratory levels

Note: Do not combine any prescription drugs unless you have received medical advice.

Treatment Options For Polysubstance Abuse

Treatment options for polysubstance abuse, which is a term used to refer to abuse of multiple substances, include:

Dual Diagnosis Treatment

Dual diagnosis treatment includes treating addiction and mental health issues, mood disorders, anxiety disorders, and personality disorders.

It is also important to assess for psychosis or drug-induced psychosis symptoms, as these may require immediate medical attention.

Medically Monitored Detox

This involves weaning a person off each substance individually and under medical supervision, usually in an inpatient setting such as a hospital or residential treatment center.

Never attempt detoxing from Xanax at home due to serious withdrawal symptoms that can occur from sudden cessation of multiple substances, especially if taken together frequently or in high doses.

Medication-Assisted Treatment

This is a form of treatment that uses medications to help with withdrawal symptoms and cravings for substances, which may help reduce or eliminate use.

The most common medications used in MAT are antidepressants, methadone and buprenorphine for opioid addiction, and naltrexone, used to reduce the effects of alcohol.

Find Treatment For Xanax Addiction At Bedrock Recovery Center

Are you or your loved one facing addiction to Xanax? If so, we at Bedrock Recovery Center can help.

Our treatment center offers a variety of effective addiction treatment programs for people with addiction and co-occurring disorders.

Call us today to learn more about our treatment programs for Xanax addiction.

  1. Government of the District of Columbia Department of Health https://doh.dc.gov/sites/default/files/dc/sites/doh/publication/attachments/Medical%20Cannabis%20Adverse%20Effects%20and%20Drug%20Interactions_0.pdf
  2. National Library of Medicine https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846112/

Written by Bedrock Recovery Center Editorial Team

© 2024 Bedrock Recovery Center | All Rights Reserved

* This page does not provide medical advice.

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